Intracerebral hemorrhage after intravenous recombinant tissue plasminogen activator for acute cerebral infarction
10.3760/cma.j.issn.1673-4165.2010.02.007
- VernacularTitle:急性脑梗死患者重组组织型纤溶酶原激活物静脉溶栓后脑出血
- Author:
Yikun GUO
;
Yansheng LI
- Publication Type:Journal Article
- Keywords:
Stroke;
Brain iachemia;
Tissue plasminogen activator;
Thrombolytic therapy;
Cerebral hemorrhage
- From:
International Journal of Cerebrovascular Diseases
2010;18(2):113-118
- CountryChina
- Language:Chinese
-
Abstract:
Intravenous recombinant tissue plasminogen activator (rtPA) thrombolysis is the most effective therapy for acute ischemic stroke. Its most serious complication is symptomatic intracerebral hemorrhage. The overall incidence reported in the literature is 6%. It is correlated with the wascular injury and the increased vascular permeability. Some clinical features, imaging and laboratory tests can predict the risks of the complication of intracerebral hemorrhage. The mortality and disability are very high in patients with the complications of intracerebral hemorrhage after thrombolytic therapy, and their prognosis is very poor. This article reviews the classification, incidence, predictive factors, and prognosis of intracerebral hemorrhage after thrombolysis.
