Progress of pathogenesis of aplastic anemia
10.3760/cma.j.issn.1673-4408.2010.02.007
- VernacularTitle:再生障碍性贫血发病机制的研究进展
- Author:
Fang WANG
;
Runming JIN
- Publication Type:Journal Article
- Keywords:
Aplastic anemia;
Pancytopenia;
Hematopoietic stem cells;
Immune disorders
- From:
International Journal of Pediatrics
2010;37(2):128-131
- CountryChina
- Language:Chinese
-
Abstract:
Aplastic anemia is an acquired bone marrow failure syndrome,characterized by an empty bone marrow,pancytopenia,as well as anemia,bleeding,infection syndrome.The pathogenesis of aplastic anemia has not yet been completely clear.Some of the proposed causes include hematopoietic stem/ progenitor cell deficiency,immune disorders,and abnormalities in the hematopoietic microenvironment.In recent years,further clinical and experimental studies have accumulated to recognize the pathogenesis of aplastic anemia.
