Progress in the role of connexin43 in ventricular arrhythmias
10.3760/cma.j.issn.1673-4408.2010.02.017
- VernacularTitle:Cx43在室性心律失常中的作用研究进展
- Author:
Yonghua YUAN
;
Yibing FANG
;
Xuehua HE
- Publication Type:Journal Article
- Keywords:
Connexin43;
Arrhythmias;
Cardiac muscle
- From:
International Journal of Pediatrics
2010;37(2):161-163
- CountryChina
- Language:Chinese
-
Abstract:
Connexin43,the base of electrical and intercellular chemical signal communication in the myocardial cell,can promote the growth and development of the heart.The decreasing of the number of connexin 43 and its' distribution changes may lead to the changing of the conduction velocity and direction,meanwhile,increase the occurrence of ventricular arrhythmias.Mesenchymal stem cells transplantation and drug therapy can improve the levels and distribution of connexin43 in ill myocardium,and can reduce the occurrence of ventricular arrhythmias.
