Progress of severe hand-foot-mouth disease infected by EV71 virus
10.3760/cma.j.issn.1673-4408.2010.02.029
- VernacularTitle:EV71感染致重症手足口病的研究进展
- Author:
Kun YANG
;
Dongchi ZHAO
- Publication Type:Journal Article
- Keywords:
Enterovirus71;
Hand-foot-mouth disease;
Central nervous system;
Neurogenic pulmonary edema
- From:
International Journal of Pediatrics
2010;37(2):199-202
- CountryChina
- Language:Chinese
-
Abstract:
Enterovirus 71(EV71),a member of human enterovirus family,was first isolated from faeces of a central nervous system infected infant in 1969.In recent 30 years,EV71 outbreaks every 2-3 years in the Asia-Pacific regions,and is the main pathogen causing severe hand-foot-mouth disease(HFMD).Severe HFMD caused by EV71 involves in central nervous system and respiratory system disorder.In general,EV71 associated complication is related to the viral invasion of central nervous system,leads to pulmonary edema or pulmonary hemorrhage.It is of great significance to study the clinical features and pathogenesis of EV71 infection,and then take positive and effective measures to block the occurrence of its complications.
