Assessments of correlation between intima-media thickness and elasticity of carotid in patients with type 2 diabetes accompanied hyperlipidemia
10.3760/cma.j.issn.1004-4477.2010.03.009
- VernacularTitle:2型糖尿病合并高脂血症患者颈动脉内膜-中层厚度与动脉弹性的相关性研究
- Author:
Chunpeng ZOU
;
Xiaoying WU
;
Pintong HUANG
;
Yimei YIN
;
Huipei JIN
;
Haiyan SUN
;
Yaping ZHAO
;
Liang WANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Diabetes mellitus,type 2;
Hyperlipidemias;
Carotid arteries;
Elasticity;
Intima-media thickness
- From:
Chinese Journal of Ultrasonography
2010;19(3):212-215
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between intima-media thickness(IMT)and elasticity of carotid in patients with type 2 diabetes accompanied hyperlipidemia by quantitative intima-media thickness(QIMT)and quantitative arterial stiffness(QAS)technique.Methods Fifty-six patients with type 2 diabetes accompanied hyperlipidemia were involved into the study as case group.Forty-eight healthy volunteers were supplied as normal control group in the same period.IMT,compliance coefficient(CC),distensibility coefficient(DC)and stiffness index(β)of carotid were acquired through QIMT and QAS.Case group was divided into case group 1(IMT＜0.9mm)and case group 2(IMT≥0.9 mm),and analysis was performed furtherly.Results β,triglyceride(TG),lowdensity lipoprotein(LDL),cholesterol(Ch),glycosylated hemoglobin(GHb)and IMT had significant differences in case group 1,case group 2 and control group(P＜0.05),control group＜case group 1＜case group 2.DC and CC had significant differences in case group 1,case group 2 and control group(P＜0.05),control group＞case group 1＞case group 2.There was significant positive correlation between β and age,GHb,LDL and IMT of carotid respectively(r=0.811,r:0.764,r=0.732,r:0.729,respectively,P=0.000).Conchmions IMT of carotid could be measured accurately by QIMT.Structure imaging and functional imaging of carotid might be combined organically through QIMT and QAS.Depth study about early change of carotid in structure and function could be performed with these two techniques.
