Effects of Xiaoke Wan on serum adiponectin levels in patients with type 2 diabetes mellitus

VernacularTitle:消渴丸对2型糖尿病血清脂联素水平的影响
Author: Shan LI
Publication Type:Journal Article
Keywords: Xiaoke Wan; Type 2 diabetes meilitus; Deficiency of both qi and yin syndrome; Adiponectin
From: International Journal of Traditional Chinese Medicine 2010;32(2):112-114
CountryChina
Language:Chinese
Abstract: Objective To investigate the effects of Xiaoke Wan on serum adiponectin levels in patients with type 2 diabetes metlitus. Methods A total of 60 2TDM patients with deficiency of both qi and yin syndrome were recruited into a control group and a treatment group randomly, 30 cases in each group. The treatment group was treated with Xiaoke Wan, and the control group was treated with glibenclamide. After 32 weeks, the changes of FPG, 2hPG, HbAIc, FINS, C-P, APN, HBCI,IRI and improvement of symptoms were compared between the two groups. Results Compared with glibenclamide, Xiaoke Wan can significantly improve the patients' symptoms, reduce the level of IRI (t=-1.590, P=-0.036), and increase serum APN (t=1.918, P=0.002). Conclusion Xiaoke Wan can significantly improve symptoms, reduce fasting blood glucose and 2 hour postprandial blood glucose, recover the secretion of adipouectin, decrease insulin resistance in 2TDM patients with deficiency of both qi and yin.