The feature, diagnosis, and treatment of fulminant type 1 diabetes
10.3760/cma.j.issn.1000-6699.2010.03.002
- VernacularTitle:暴发性1型糖尿病的特点与诊治
- Author:
Jianmin LIU
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 1;
Fulminant diabetes mellitus;
Diagnosis;
Therapy
- From:
Chinese Journal of Endocrinology and Metabolism
2010;26(3):181-182
- CountryChina
- Language:Chinese
-
Abstract:
Type 1 diabetes includes two categories:autoimmune (type 1A) and idiopathic (type 1B)diabetes.Fulminant type 1 diabetes is a recently discovered subtype of type 1 diabetes with extremely rapid progression of hyperglycemia and ketoacidosis.The prevalence of fulminant type 1 diabetes among acute-onset type 1 diabetic patients is around 15%-20%.Class Ⅱ HLA genotype and virus infection may contribute to its development.The near-normal HbA_(1C) level despite a very high plasma glucose concentration in patients with ketoacidosis is the clue to diagnosis of fulminant type 1 diabetes.Treatment must be started immediately and aggressively when the diagnosis of fulminant type 1 diabetes is made or strongly suspected.