Application of MRI in severity grading and activity staging in thyroid associated ophthalmopathy
10.3760/cma.j.issn.1000-6699.2010.03.012
- VernacularTitle:MRI在甲状腺相关眼病分级和分期的应用
- Author:
Qingshan HONG
;
Jie SHEN
;
Yaoming XUE
;
Yanping CHEN
;
Zhichun UN
- Publication Type:Journal Article
- Keywords:
Thyroid associated ophthalmopathy;
NOSPECS scores;
Clinical activity;
Magnetic resonance imaging
- From:
Chinese Journal of Endocrinology and Metabolism
2010;26(3):215-216
- CountryChina
- Language:Chinese
-
Abstract:
The influence of MRI on severity grading and activity staging in thyroid associated ophthalmopathy (TAO) was evaluated.The results showed that MRI had a higher detection rate in abnormal extraocular muscle than NOSPECS scores(χ~2 = 19.37,P = 0.000).MRI had higher sensitivity,specificity,and accuracy in detection of active TAO than clinical activity score (100% vs 95.7%,88.2% vs 35.3%,96.9% vs 79.7%,respectively).Therefore,MRI improves early detection of atypical grade 4 cases.Signal intensity elevation in adipose suppressed T2WI is helpful to define active stage.
