Observation on the treatment of recurrent oral ulcer with the combination of vitamin B2 and Zhibaidihuangwan
10.3760/cma.j.issn.1673-4246.2010.03.029
- VernacularTitle:知柏地黄丸联合维生素B2治疗复发性口腔溃疡的疗效观察
- Author:
Lingqiu MENG
;
Xiaoran YANG
;
Zhifeng YANG
- Publication Type:Journal Article
- Keywords:
Zhibai-Dihuang Wan;
Recurrent oral ulcer
- From:
International Journal of Traditional Chinese Medicine
2010;32(3):239-240
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of combined vitamin therapy of B2 and Zhibai-Dihuang Wan on recurrent oral ulcer.Methods A total of 178 patients with recurrent oral ulcer were randomly recruited into a control group and a treatment group.The control group was treated with vitamin B2,0.2g/time,3 times/day;while the treatment group WaS treated with Zhibai-Dihuang Wan,9g/time,twice/day,on the basis of the control group.The therapeutic effects were observed in both groups after 14 days.Results The obvious effective rate in the treatment group was significantly higher than the control group(P=0.0083).while total effective rate did not show significant difierence between the two groups(P=0.0712).The relapse rate in the treatment group was significant lower than the control group.Conclusion It is effective to treat recurrent oral ulcer with the combination of vitamin B2 and Zhibai-Dihuang Wan.