Progress of innate immunity defect disease
10.3760/cma.j.issn.1673-4408.2010.03.013
- VernacularTitle:天然免疫缺陷病的研究进展
- Author:
Hui ZHANG
- Publication Type:Journal Article
- Keywords:
Primary immunodeficiency disease;
Defects in innate immunity
- From:
International Journal of Pediatrics
2010;37(3):261-263
- CountryChina
- Language:Chinese
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Abstract:
Pritnaiy immunodeficiency diseases can be divided into eight diseases, including defects in innate immunity. According to new literature,defects in innate immunity involves seven diseases which are all resulted from gene mutation. Three diseases have a correlation with NF-κB signaling pathway. Different from common primary immunodeficiency diseases, two diseases have a correlation with virus infection. Defects in innate immunity play an important role in primary immunodeficiency diseases. But it can't make a definite diagnosis because of incompletely understanding.
