Advance in immunopathogenesis for systemic lupus erythematosus
10.3760/cma.j.issn.1673-4408.2010.03.015
- VernacularTitle:系统性红斑狼疮的免疫学发病机制研究进展
- Author:
Ting LIU
- Publication Type:Journal Article
- Keywords:
Systemic lupus erythematosus;
Adaptive immune deficiency;
Inherent immunity defect;
Complement deficiency
- From:
International Journal of Pediatrics
2010;37(3):267-269
- CountryChina
- Language:Chinese
-
Abstract:
Systemic lupus erythematosus is a typical autoimmune disease commonly seen in childhood, the immunnopathogenesis of which is complicated. Along with the rapid advances of immunology and molecular biology, all the associated research has found that the onset of systemic lupus erythematosus is associated with dysfunction of T cells and B cells. They focus on the break of the normal autoimmune immunity and the form of malgenic autoantibody. It is also connected with primary immunodeficiency. The dysfunction of inherent immunity contributes to the break of autoimmune and the progression of the disease.
