Advances in study of microRNAs in gliomas
10.3760/cma.j.issn.1673-422X.2010.03.013
- VernacularTitle:胶质瘤中微RNA研究进展
- Author:
Jianwei HAO
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Glioma
- From:
Journal of International Oncology
2010;37(3):200-203
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs(miRNAs or miR)are a class of endogenous noncoding RNAs,average～22 nt in length. MiRs negatively regulate gene expression at post-transcription level and the dysregulation of miRs is closely correlated with tumorigenesis.The present paper introduces the recent studies of aberration of miRs and its possible mechanisms in gliomagenesis,which will be helpful in further understanding the molecular pathology,developmemt of diagnostic biomarkers and new therapeutic strategies for gliomas.
