Expression of tight junctions protein regulator PKC-θ in meningioma tissue
10.3760/cma.j.issn.1673-422X.2010.03.022
- VernacularTitle:蛋白激酶C-θ在脑膜瘤组织中的表达
- Author:
Guangchao ZHANG
;
Xiaoqiu YANG
;
Guofeng JIANG
;
Yingwei LIU
;
Chenshi QUAN
- Publication Type:Journal Article
- Keywords:
Meningioma;
Protein kirtase C
- From:
Journal of International Oncology
2010;37(3):228-229
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression and clinical meaning of tight junctions protein regulator PKC θ in human meningioma tissue.Method The expression of PKC θ in 30 non-invasion and 30 invasion meningioma tissue is tested by using immunohistochemistry S-P method,with the goal of analyzing the relationship between the expression of PKC θ and pathology character.Results The positive rate ofPKC θ in invasion meningioma tissue is obviously lower than in non-invasion meningioma tissue.The difference is significant(P<0.05)Conclusions The lower expression of PKC θ in invasion meningioma tissue pmbably affects occurrence and invasion of the meningioma by ehang4ng the structure and function of TJs.
