Cognitive change in schizophrenic patients with concomitant metabolism syndrome
10.3760/cma.j.issn.1674-6554.2010.04.011
- VernacularTitle:伴发代谢综合征精神分裂症患者认知功能变化
- Author:
Qinyun LI
;
Qingtao BIAN
;
Yizhuang ZOU
;
Jian WANG
;
Guanghui ZHANG
;
Weishan WANG
;
Xiaopeng LIU
;
Shouzi ZHANG
;
Lixia ZHANG
;
Yunlong TAN
;
Shuping TAN
;
Jiefeng CUI
;
Nan CHEN
;
Hongzhen FAN
- Publication Type:Journal Article
- Keywords:
Metabolism syndrome;
Schizophrenia;
Cognitive function
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2010;19(4):322-324
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore cognitive change in schizophrenic patients with concomitant metabolism syndrome,and to provide theory basis for early intervention and treatment.Methods According to inclusion standard,56 schizophrenic inpatients with metabolism syndrome and 56 schizophrenic inpatients without metabolism syndrome were included.The matrics consensus cognitive battery(MCCB),stroop test,digit span,UPSA-B were used to assess the cognitive function.Results There were significant differences for test scores of symbol coding subtest,verbal memory subtest,digit sequence subtest,Maze subtest,continue performance among MCCB between schizophrenic patients with and without metabolism syndrome(27.07±10.46 vs 32.18±12.12,16.04±5.07 vs18.71±6.02,13.39±5.18 vs 15.79±5.48,1.38±0.66 vs 1.7±0.68,all P＜0.05),as well as stroop test and digit span test(31.14±11.68 vs 36.57±13.32,13.77±3.64 vs 15.82±4.38,P＜0.05 for both).Conclusion The schizophrenic patients with metabolism syndrome have severer cognitive impairment than those without metabolism syndrome.
