Two Cases of Cytomegalovirus Retinitis as a Manifestation of Good's Syndrome.
- Author:
Hye In KIM
1
;
Hyun Ha CHANG
;
Ga Young PARK
;
Eu Gene KWON
;
Hyo Hoon KIM
;
Shin Woo KIM
;
Jong Myung LEE
Author Information
1. Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea. changhha@knu.ac.kr
- Publication Type:Case Report
- Keywords:
Cytomegalovirus retinitis;
Immunologic deficiency syndromes;
Thymoma
- MeSH:
Adult;
Cytomegalovirus;
Cytomegalovirus Retinitis;
Female;
Humans;
Immunologic Deficiency Syndromes;
Korea;
Middle Aged;
Paraneoplastic Syndromes;
Pneumonia;
Retinitis;
T-Lymphocytes;
Thymectomy;
Thymoma;
Tuberculosis;
Tuberculosis, Pulmonary
- From:Korean Journal of Medicine
2011;81(2):266-274
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Good's syndrome (GS) is a rare cause of acquired combined B- and T-cell immunodeficiency in adults. GS is also known as a rare form of paraneoplastic syndrome of thymoma that may persist after thymectomy. Some reported GS cases have been related to various diseases as a result of humoral immunodeficiency, but no report to date has related GS to cytomegalovirus (CMV) retinitis in Korea. We report two cases of CMV retinitis as a manifestation of GS with severe cellular immunodeficiency. In the first case, a 61-year-old woman was diagnosed with GS manifesting as CMV retinitis combined with coincident pulmonary tuberculosis and soft-tissue tuberculosis. In the second case, a 56-year-old man had CMV retinitis and CMV pneumonia. Both patients had a history of thymoma and had received total thymectomies, and were diagnosed with GS a few years thereafter.
