Ezrin and tumor metastasis
10.3760/cma.j.issn.1673-422X.2010.03.003
- VernacularTitle:埃兹蛋白与肿瘤转移
- Author:
Zhengke PENG
- Publication Type:Journal Article
- Keywords:
Phosphoproteins;
Neoplasm metastasis
- From:
Journal of International Oncology
2010;37(3):170-172
- CountryChina
- Language:Chinese
-
Abstract:
Ezrin is a member of ezrin-radixin-moesin(ERM)family acting as correlationship between plasma membrane and cytoskeleton,which plays an important role in maintaining shape,polarity,and movement as well as signal transduction of cells.The recent studies indicate that Ezrin abnormally overexpresses in majority of tumor cells,which has close relationship with carcinogenesis,invading and metastasis of tumor cells.