The effects of aloe juice on SOD, GSH-PX , MDA and skin wound healing in scalded rats
10.3760/cma.j.issn.1008-1372.2010.04.010
- VernacularTitle:芦荟汁对烫伤大鼠皮肤的愈合及SOD、MDA及GSH-PX的影响
- Author:
Junyi YE
;
Jiarong ZHU
;
Li WANG
;
Yin TU
;
Fuli YAO
;
Keying WANG
- Publication Type:Journal Article
- Keywords:
ALOE△/PD;
Burns/DT;
Wound healing/DE;
Superoxide dismutase/ME/DE;
Malondialdehyde/ME/DE;
Glutathione peroxidase/ME/DE
- From:
Journal of Chinese Physician
2010;12(4):459-461
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of aloe juice on skin wound healing in scalded rats and scavenging the oxygen free radical in their bodies. Methods 24 rats were divided into 3 groups,namely, aloe group, burn cream group and blank control group. And burn wounds ( Ⅱ degree deep) were created with a diameter of 2. 6cm in their backs, respectively. Smear Burn Ointment and Aloe Vera juice,were used to observe the time of the appearance of their epithelial tissues and the time of the wound healing,and the content of SOD, GSH-PX and MDA in healed skin surfaces were detected. Results The time of the appearance of epithelial tissues[(4.6 ±0. 56)d ,(16.2±2.6),(5.4±0.6)d,(18. 1 ±3.4)d,(6.8± 0. 3) d , (22. 3 ± 3.2 ) d], the wound healing and the content of SOD [( (98.07 ± 6. 22) vs(83.97 ± 6. 34), (57. 50 ± 9. 43 )], GSH-PX [(243.21 ± 20. 18)vs (208.25 ± 24. 52), ( 139. 88 ± 22. 70)] and MDA [(4. 89 ±2. 12) vs (6. 93 ± 3.05 ), (8.98 ± 2. 14)] in aloe group have significant difference compared with the blank group( P <0.01, 0.001, 0.005), but no significant difference compared with the burn cream group. Conclusion Aloe juice has the effects of promoting the skin wound healing of scalded rats ,scavenging the oxygen free radical in their bodies and protecting cells.
