Cytokines and their relationship to the symptoms and outcome of cancer
10.3760/cma.j.issn.1673-422X.2010.03.009
- VernacularTitle:细胞因子与肿瘤临床表现及转归的关系
- Author:
Xiaoge KOU
;
Mingyao LIU
- Publication Type:Journal Article
- Keywords:
Cytokines;
Neoplasms
- From:
Journal of International Oncology
2010;37(3):188-190
- CountryChina
- Language:Chinese
-
Abstract:
Cytokines can have either pro-or anti-inflammatory activity and immunosuppressive activity,depending on the microenvironment.Tumors contain immune cells and a network of pro-and anti-inflammatory cytokines,which collaborate in the development and progression of cancer.Cytokine might prove to be prognostic.The systemic effects of pro-inflammatory cytokines are associated with fatigue,depression,cognitive impairment,anorexia,cachexia,pain,toxicity of treatment and resistance to treatment,which can affect quality of life.