Clinical observation on effects of Qingjiefang on early diabetic nephropathy and insulin resistance

VernacularTitle:清解方用于胰岛素抵抗及早期糖尿病肾病的临床观察
Author: Wenwen CHEN ; Xiaowei XU ; Dexian ZHANG ; Wenli PANG ; Baogang SHI ; Lili JIANG ; Lu TAO
Publication Type:Journal Article
Keywords: Traditional Chinese medical thempy; Qingrejiedu therapy; Insulin resistance; Diabetic nephropathy
From: International Journal of Traditional Chinese Medicine 2010;32(3):232-233
CountryChina
Language:Chinese
Abstract: Objective To observe the effects of Qingjiefang on insulin resistance and reduction of microalbuminuria in early diabetic nephropathy.Methods A total of 64 patients with early diabetic nephropathy were randomly recruited into a control group and a treatment group.The control group(32 cases)was treated with conventional western medicine,while the treatment group(32 cases)was treated with Qingjiefang based on the control group.The changes of the fasting plasma glucose(FPG),2hBG,glycosylated hemoglobin(HbAlC),fasting Insulin(FINS),24 hours urinary albumin excretion rate (UAER).body mass index(BMI)and insulin resistance(IR)were observed before and after the treatment.Results After the treatment,FINS,IR and UAER were decreased in the treatment group,the comparison with the control group showed significant difference (P<0.05).Conclusion Qingjiefang can effectively improve insulin resistance and prevent early diabetic nephropathy.