Clinical feature of the non-motor symptoms of Parkinson's disease

VernacularTitle:帕金森病非运动症状的特征研究
Author: Ning ZHANG ; Weiguo LIU ; Min YE ; Yingdong ZHANG
Publication Type:Journal Article
Keywords: Parkinson's disease; Non-motor symptom; Scales
From: Chinese Journal of Behavioral Medicine and Brain Science 2010;19(4):331-333
CountryChina
Language:Chinese
Abstract: Objective To survey the prevalence,distribution of non-motor symptoms(NMS)in different H-Y stage of Parkinson diseases(PD)and some correlative factors of NMS.Methods 169 patients with PD and 102 controls were involved in the survey.Parkinson diseases rating scale Ⅲ(UPDRS-Ⅲ)and Ⅴ(UPDRS-Ⅴ),Non-Motor Symptoms Questionnaire for Parkinson's disease(NMSQuest),Hamilton depression scale(HAMD),Hamilton Anxiety Scale(HAMA),Parkinson's Disease Sleep Scale(PDSS)and Mini-Mental State Examination (MMSE)were used to assess motor and non-motor symptoms.Results Most patients had non-motor symptoms (99.41%),including depressive symptoms(76.33%)and anxious symptoms(80.47%).The scores of HAMA,HAMD,PDSS and NMSQuest of patients were significant different from those of the controls.There were significant different between the different H-Y stages on the distribution and severity of NMS.The HAMA,the H-Y stage,PDSS,gender and MMSE had entered the regression equation.Conclusion NMS in PD are common and frequent.There are different clinical characteristics on the distribution and severity of NMS between the different H-Y stages.