Genetics of pubertal timing
10.3760/cma.j.issn.1673-4408.2010.03.010
- VernacularTitle:遗传因素对青春期启动时间的调控
- Author:
Xiaoyu MA
- Publication Type:Journal Article
- Keywords:
Genetic regulation;
Genetics;
Puberty;
Idiopathic hypogonadotropic hypogonadism;
Kallmann syndrome
- From:
International Journal of Pediatrics
2010;37(3):251-253
- CountryChina
- Language:Chinese
-
Abstract:
Puberty is an important developmental stage that leads to sexual maturation and reproductive capability. Genetic factors play a significant role in regulating the variation of pubertal timing. Recent genetic analysis are increasingly elucidating the genetic basis of disorders of pubertal timing such as hypogonadotropic hypogonadism and Kallmann syndrome. Ongoing studies are also investigating the genetic control of puberty in the general population, although no genetic loci have been reproducibly associated with pubertal timing thus far. This review summarizes an update of the genes implicated in disorders of puberty,discusses genes that may be involved in the timing of normal puberty.
