Treatment of transplanted renal artery stenosis with percutaneous transluminal angioplastly
10.3760/cma.j.issn.0254-1785.2010.05.006
- VernacularTitle:经皮血管成形术治疗移植肾动脉狭窄的临床研究
- Author:
Ming ZHAO
;
Jianmin HU
;
Ying GUO
;
Liangsheng YUE
;
Lipei FAN
;
Hua CHEN
;
Min LI
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Renal artery obstruction;
Angioplasty,balloon
- From:
Chinese Journal of Organ Transplantation
2010;31(5):276-279
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of percutaneous transluminal angioplasty (PTA) in the treatment of transplanted renal artery stenosis (TRAS)-induced renal dysfunction and hypertension. Methods Between July 1998 and January 2007, PTA was performed on 16 patients with RTAS. Color Doppler uhrasonography preceded the intra-arterial angiographic investigation,with false-negative results in 18. 75 % of patients. Sixteen cases of TRAS were examined at 1 st week,6th month and 13 years after PTA. Hypertension improvement was defined as mean arterial pressure decrease of at least 15 % from the pre-PTA value. Graft function was evaluated by SCr levels, and the improvement was defined as a 20% change. Results Angioplasty was technically feasible in 100 %.Sixteen patients with RTAS were cured clinically. During the follow-up period, graft function was improved in 81.25 %, 68. 75 %, 62. 5 %, 56. 25 %, 50 % of patients respectively at 1st week, 6th month and 1-3 years after PTA. The blood pressure was decreased in 62. 5%, 75 %, 75 %,56. 25 %, 50 % of patients respectively, but no patient remained hypotensor medication free.Conclusion PTA improved renal dysfunction and hypertension induced by TRAS, and it is a safe and effective treatment for TRAS.