Progress on proteome of rheumatoid arthritis
10.3760/cma.j.issn.1673-4408.2010.03.006
- VernacularTitle:类风湿关节炎蛋白质组学研究进展
- Author:
Leying HUO
- Publication Type:Journal Article
- Keywords:
Arthritis;
Rheumatoid;
Proteomics
- From:
International Journal of Pediatrics
2010;37(3):240-242
- CountryChina
- Language:Chinese
-
Abstract:
Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting joints. Proteomics is a new field of studying the protein and its dynamic axiom of transmutation in cells. Two-dimensional gel electrophoresis, mass spectrometry and bioinformatics are the three major technology. Recently,the research in rheumatoid arthritis proteomics has made great progress. Application of proteomics technology is designed to study the pathogenesis from the proteins levels,finding out the marker proteins in order to improue RA diagnosis, treatment and prognosis.