Progress in relationship between inhibitor of apoptosis protein Livin and tumors
10.3760/cma.j.issn.1673-4408.2010.03.018
- VernacularTitle:凋亡抑制蛋白Livin与肿瘤关系的研究进展
- Author:
Shaohua XIE
- Publication Type:Journal Article
- Keywords:
Inhibitor of apoptosis protein;
Livin;
Tumors
- From:
International Journal of Pediatrics
2010;37(3):276-279
- CountryChina
- Language:Chinese
-
Abstract:
Livin is a newly discovered member of the inhibitor of apoptosis protein family. Its antd-apoptosis function is mainly by inhibiting of casepases protein. So far, the over expression of Iivin has been detected in many malignant tumors.Research showed that Iivin may play a role in the progress of carcinogenesis of tumors and also be related with the resistance and the prognosis.Livin may serve as a new target for tumros diagnosis and treatment.In this review, we will summarize the new development in the relationship of Iivin and tumors in recent years.