Diagnostic effect and influential factors of intro-operative tissue puncture biopsy for mass in pancreatic head
10.3760/cma.j.issn.1007-8118.2010.05.001
- VernacularTitle:胰头占位术中组织学穿刺活检的诊断效果与影响因素
- Author:
Yan ZHUANG
;
Yinmo YANG
;
Hongqiao GAO
;
Weimin WANG
;
Yuanlian WAN
- Publication Type:Journal Article
- Keywords:
Pancreatic neoplasms;
Tissue biopsy;
Intro-operative puncture;
Pancreatic fibrosis
- From:
Chinese Journal of Hepatobiliary Surgery
2010;16(5):321-324
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic effect of intro-operative tissue puncture biopsy and find its influential factors.Methods The clinical data of 94 patients with pancreatic mass treated in our hospital from July 1994 to December 2007 and undergoing intro-operative tissue puncture biopsy were retrospectively analyzed.Results The sensitivity,the specificity,the positive predictive value and the negative predictive value were 74.6%,93.8%,98.0%and 46.9%,respectively.The single factor analysis showed that the size of pancreatic mass,the number of puncture and complicating with pancreatic fibrosis or not were related to the diagnosis of tissue puncture.The multiple factor analysis showed that the size of pancreatic mass(P=0.014)and the number of puncture(P=0.020)were crucial to the diagnosis of puncture.The sensitivity and specificity of intro-operative tissue puncture biopsy for the pancreatic mass less than 25 mm were lower than that for the mass larger than 25 mm (P=0.000).The sensitivity and specificity would be increased as the number of puncture increased (P=0.000).For the mass less than 25 mm,increasing the humber of puncture would improve the sensitivity(P=0.002).Conclusion Intro-operative tissue puncture biopsy is a simple and accurate procedure for differentiating the pancreatic mass.The sensitivity and specificity could be improved by increasing the number of puncture,especially for the patients with pancreatic mass less than 25 mm.
