Lymphoepithelioma-like carcinoma of the ureter(a case report and literature review)

VernacularTitle:原发性输尿管淋巴上皮样癌一例报告并文献复习
Author: Xingcheng WU ; Hanzhong LI ; Weigang YAN ; Yushi ZHANG
Publication Type:Journal Article
Keywords: Ureter; Renal pelvis; Urothelial carcinoma; Lymphoepithelioma-like; Histopathology
From: Chinese Journal of Urology 2010;31(5):319-321
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical presentations,pathologic features,treatment and prognosis of lymphoepithelioma-like carcinoma(LELC)in the upper urinary tract. Methods A case with LELC of the ureter was retrospectively analyzed.A 81-year-old female patient was hospitalized because of gross hematuria for 1 month. CTU demonstrated a 2.5cm tumor in the left ureter.Radical nephroureterectomy was performed laparoscopically. Results Pathologic findings showed invasive poorly differentiated carcinoma in a prominent lymphocytic background.The diagnosis was LELC of the ureter.Epstein-Barr virus in situ hybridization was negative.No disease progression was noted at 3-month foUow-up. Conclusions LELC of the upper urinary tract is rare.All the cases are diagnosed pathologically.The disease eould be treated with radical surgery.Although the differentiation of the tumour cells is poor,the prognosis of pure subtypes seems to be better than that of other types of urothelial carcinoma.