Parametric imaging of contrast-enhanced ultrasound for hepatocellular carcinoma
10.3760/cma.j.issn.1004-4477.2010.05.010
- VernacularTitle:肝细胞性肝癌超声造影参数成像临床应用研究
- Author:
Manxia LIN
;
Huixiong XU
;
Xiaoyan XIE
;
Mingde Lü
;
Zuofeng XU
;
Guangjian LIU
;
Xiaohua XIE
;
Lida CHEN
;
Bei HUANG
;
Mianni CHEN
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Carcinoma,hepatocellular;
Parametric image
- From:Chinese Journal of Ultrasonography
2010;19(5):393-396
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the usefulness of parametric imaging of contrast-enhanced ultrasound(CEUS) in imaging hepatocellular carcinoma (HCC) using dynamic vascular patterns (DVP). Methods Thirty clinically or pathologically proven HCCs that had undergone CEUS were randomly included. SonoLiver CAP sofeware was used to analyze the CEUS images and reconstruct DVP parametric images. Results The rise time, time to peak and mean transit time were (16. 72±11. 07) s, (29. 92±14. 13) s,(115. 03±90. 91)s in HCC versus (26. 59±9. 60) s, (41.67±12. 59) s, (159.26±123. 74) s in the surrounding liver parenchyma (all P <0. 05). The perfusion index was (90. 41±102. 49) % in HCC versus (54. 10±24. 99)% in surrounding liver parenchyma( P = 0.044). DVP curve and DVP parametric image could both be divided into three types:washout,non-washout and cystic type. The percentages of which were 76.7% (23/30), 20.0% (6/30) and 3.3% (1/30) in DVP curves, respectively, and 66.7% (20/30), 30.0% (9/30) and 3.3% (1/30) in DVP parametric images,respectively. Conclusions Parametric image of CEUS could demonstrates the difference of flow perfusion static between HCC and surrounding liver parenchyma dynamically and directly.
