Study on the risk of metabolic syndrome in women with polycystic ovary syndrome
10.3760/cma.j.issn.1000-6699.2010.05.002
- VernacularTitle:多囊卵巢综合征患者代谢综合征患病风险研究
- Author:
Qun YAN
;
Jie HONG
;
Weiqiong GU
;
Yifei ZHANG
;
Yuwen ZHANG
;
Juan SHI
;
Weiqing WANG
;
Xiaoying LI
;
Guang NING
- Publication Type:Journal Article
- Keywords:
Polycystic ovary syndrome;
Metabolic syndrome;
Obesity;
Insulin resistance
- From:
Chinese Journal of Endocrinology and Metabolism
2010;26(5):351-354
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the prevalence of metabolic syndrome (MS) in women with polycystic ovary syndrome (PCOS) ,and to explore the risk factors of MS in young women. Methods The prevalence of MS and its components were evaluated in 348 young women with PCOS and 113 control subjects without PCOS. Results According to the 2005 modified Adult Treatment Panel Ⅲ criteria,MS was found in 27.0% of PCOS women,being significantly higher than 10.6% in the controls(P<0.01). The rates of MS components,except for the triglyceride (TG) level, were all significantly higher in PCOS subjects than those in control subjects ( P < 0. 05 or P < 0.01). However, the difference disappeared after adjustment for age and body mass index ( BMI, P>0. 05). The results of logistic regression analysis revealed that homeostasis model assessment insulin resistance (HOMA-IR)and BMI were the independent predictors of MS( both P<0.01) ,and the presence of PCOS was not the independent risk factor for MS (P>0. 05). Conclusions Obesity and insulin resistance are the independent predictors of MS. PCOS alone does not increase the risk of MS prevalence.
