Evaluation of grey scale ultrasonography combined with elastography in differentiating benign and malignant thyroid lesions using receiver operating characteristic curves
10.3760/cma.j.issn.1004-4477.2010.05.017
- VernacularTitle:灰阶超声联合超声弹性成像在甲状腺良恶性结节鉴别诊断中的应用价值
- Author:
Zhanwu FENG
;
Shuzhen CONG
;
Kang LI
;
Lisang WU
;
Qing CHEN
;
Kehong GAN
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Thyroid diseases;
Elastography;
ROC curve
- From:
Chinese Journal of Ultrasonography
2010;19(5):411-414
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of grey scale ultrasonography (US) combined with elastography in the difference diagnosis of benign and malignant thyroid lesions. Methods Sixty-two patients with 81 lesions were examined by grey scale US and elastography preoperatively. All the lesions were confirmed by pathology. According to their features of grey scale ultrasonograms and elastograms, two receiver operating characteristic (ROC) curves were drawn, one for gray ultrasound and one for the combination methods. The area under curve (AUC) of them were made a comparison. Results The cut-off value of the grey scale group was equal or more than 5, the sensitivity,specificity was 60. 0% ,98. 5%. And the cut-off value of grey scale US combined with elastography group was equal or more than 6, the sensitivity, specificity was 80.0%, 89.4%. The AUC of grey scale US was 0.860 and that of the combination group was 0. 916. The difference between them was statistically significant Z = - 7. 863, P = 0. 000). Conclusions The grey scale US combined with elastography could improve sensitivity and decrease omission diagnose rate. It may be more helpful in the difference diagnosis of malignant from benign thyroid lesions.
