Association of glycemic index of the mixed food with glucose and lipid metabolism index in elderly patients with type 2 diabetes mellitus
10.3760/cma.j.issn.1000-6699.2010.05.011
- VernacularTitle:混合膳血糖指数与老年2型糖尿病患者糖脂代谢的相关性
- Author:
Min ZONG
;
Jianqin SUN
;
Min CHEN
;
Yanqiu CHEN
;
Xinyi ZHANG
;
Yumiao WU
;
Kejun YANG
;
Maofang CHEN
;
Aifang CHEN
- Publication Type:Journal Article
- Keywords:
Glycemic index,mixed meal;
Blood glucose;
Body mass index;
Low-density lipoprotein cholesterol
- From:
Chinese Journal of Endocrinology and Metabolism
2010;26(5):385-387
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between glycemic index (GI) of mixed foods and glucose and lipid metabolism index in elderly patients with diabetes mellitus, and to analyze the effects of CI response with regard to sex and obesity. Methods Forty-three patients with diabetes mellitus were divided into two groups with randomly crossover methods: high CI group and low GI group. Mixed meals were given for ten weeks (washing time:2 weeks). The biochemistry index and anthropometric index at baseline,before and after the first and second phase were measured. At the same time,fasting blood glucose(FBG)and postprandial 2 h blood glucose (2hBG) were supervised thrice a week and the daily energy, three macronutrients, and GI were calculated during trial. Results GI was positively correlated with FBG, 2hBG, homeostasis model assessment of insulin resistance ( HOMA-IR) ,body mass index ( BMI), and low-density lipoprotein cholesterol ( r = 0. 097-0. 423, P = 0. 000 1-0.01). GI value was a strong associated factor for FBG and 2hBG in overweight male patients. Conclusions The GI of mixed foods can better reflect the level of glucose response, especially in obese men. And it had good correlations with other metabolic indexes.
