Effects of treating chronic pulmonary heart disease complicated with heart failure in plateau area with Shenfu injection
10.3760/cma.j.issn.1008-6315.2010.05.016
- VernacularTitle:参附注射液治疗高原地区慢性肺源性心脏病合并心力衰竭的疗效观察
- Author:
Shijun TONG
;
Ming HOU
- Publication Type:Journal Article
- Keywords:
Pulmonary heart disease;
Heart failure;
Shenfu injection
- From:
Clinical Medicine of China
2010;26(5):494-496
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the clinical effects of Shenfu injection which consists mainly of panaxoside and water-solubility alkaloied on chronic pulmonary heart disease complicated with heart failure.Methods Ninetysix patients were randomly divided into two groups ,40 patients underwent regular treatment (control group) and 56 patients were treated with Shenfu injection additionally to regular treatment (treatment group ).There were 2 treatment durations,with 15 days in one duration.The symptoms,left ventricular ejection fraction (LVEF) and B type UNa peptide (BNP) were measured before and after treatment.Results The total effective rate in the treatment group was 91.1% (51/56) ,which was significantly higher than that in the control group (72.5% ,29/40) (P ＜0.05 ).After treatment,the treatment group has significantly higher LVEF than the control group(53.27% ±7.45%vs.49.12% ± 5.89% ) ( P ＜ 0.05 ),and significantly lower BNP ( ( 209.1 ± 18.7 ) ng/L vs.( 261.2 ± 19.3 ) ng/L ( P ＜ 0.05).Conclusions Shenfu injection could strengthen the contractility and increase LVEF,therefore improve the function of left ventricle,as well as decrease BNP and repair heart failure.
