Investigation of risk factors for mild cognitive impairment in elderly people
10.3760/cma.j.issn.0254-9026.2010.05.025
- VernacularTitle:老年人轻度认知损害危险因素的调查分析
- Author:
Xinzheng LIANG
;
Yunbo WU
;
Jiaqiang LIU
;
Liyan FANG
;
Jinzhou TIAN
- Publication Type:Journal Article
- Keywords:
Mild cognitive impaiment;
Alzheimer's diseases Risk factor
- From:
Chinese Journal of Geriatrics
2010;29(5):429-431
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors for mild cognitive impairment (MCI) in elderly people in Beijing.Methods Using multistage cluster random sampling,129 elderly people aged 60-80 years living around Dongzhimen communities were interviewed by mini-mental state examination (MMSE) and National Institute of Neurological and Communicative Diseases and Stroke/ Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) criteria for screening MCI and Alzheimer's disease (AD).Results Thirty-seven cases (28.7%) had amnestic MCI (aMCI),thirty-six cases (27.9%) had AD,and fifty-six cases (43.4%) were with normal cognitive state (NCS).The age was older in aMCI patients or AD patients than in NCS[(67.6±7.5)y vs.(62.5±7.9)y,(67.6±7.5)y vs.(62.5±7.9)y,both P<0.01],Andthe aMCI or AD patients had low level of education (P<0.05).The blood pressure was higher in the patients suffered from aMCI or AD than in people with NCS more or less (P<0.05).The prevalence of aMCI was related to the body mass index (BMI) (P<0.05),while that of AD had no significant relation with BMI (P>0.05).The prevalence of aMCI or AD was not significantly different between male and female or between different birth months.(all P>0.05).Conclusions The prevalence of aMCI increases with age,lower level of education,higher level of blood pressure and BMI,while it has no significant relations with gender or birth month.
