Research advances in the let-7e biological function
10.3760/cma.j.issn.1673-4181.2010.02.010
- VernacularTitle:let-7e生物学作用的研究进展
- Author:
Yijun SONG
;
Xin TIAN
- Publication Type:Journal Article
- Keywords:
let-7e;
miRNA;
Gene regulation
- From:
International Journal of Biomedical Engineering
2010;33(2):106-108
- CountryChina
- Language:Chinese
-
Abstract:
let-7e is one member of let-7 miRNA family, a class of endogenous noncoding RNA which consists of 22 nucleotides. The recent miRNA profiles investigation and analysis results showed that let-7e could be involved in embryonic stem cells differentiation, tumorigenesis in cancer, temporal lobe epilepsy and sleep loss, lipopolysaccharide induced inflammation by regulating its target mRNA expression. This paper gives a review of the important biological function of let-7e.
