Feasibility study of the Montreal cognitive assessment of Chinese version for the detection of vascular cognitive impairment-no dementia in Han population
10.3760/cma.j.issn.1674-6554.2010.05.009
- VernacularTitle:中文版蒙特利尔认知评估表在非痴呆性血管性认知障碍筛查中的研究
- Author:
Yi WANG
;
Zhijun ZHANG
;
Chunxian YUE
;
Yuhuan TENG
;
Di WU
;
Yongmei SHI
- Publication Type:Journal Article
- Keywords:
Vascular cognitive impairment-no dementia;
Montreal Cognitive Assessment;
Screening
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2010;19(5):412-414
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore feasibility of the Chinese version of MoCA for the detection of vascular cognitive impairment-no dementia (VaCIND) and control in a cross-sectional study. Methods One hundred and three Chinese Han were assessed by the MoCA and MMSE. 64 met criteria for VaCIND and 39 were considered cognitively normal. Sensitivities and specificities were calculated using the recommended cut-off scores,and ROC curve analyses were performed to determine optimal sensitivity and specificity. Results No differences were found between groups on age,gender,education degrees. According to their MoCA scores,cognitive impairments including memory,visuospatial, executive function, attention, language, and orientation sub-scores in VaCIND ((0.44 ± 0.96), (2.13 ±1.40), (1.90 ±1.02), (4.61 ±1.41), (4.23 ±1.40), (5.38 ±1.15)) significantly decreased compared with that in controls((2.92 ± 1.42) ,(3.16 ± 1.08) ,(3.32 ± 1.07) ,(5. 87 ±0.41) ,(5.34 ±0.75), (5.79 ±0. 70)) (P<0. 05). The MMSE scale was insensitive to cognitive impairment as compared with MoCA scale. Using cut-off score of 24,the MoCA exhibited excellent sensitivity (0.923) and specificity (0.906). Conclusion MoCA is a more sensitive instrument than the MMSE for the detection of VaCIND and warrants further investigation regarding its applicability in large group and varying ethnic groups.