Prospective study of combinative artificial kidney treatment on renal osteopathy
10.3760/cma.j.issn.1008-6315.2010.05.006
- VernacularTitle:组合型人工肾治疗肾性骨病的前瞻性研究
- Author:
Yongming LIN
;
Yanping WU
;
Miaoling LI
;
Yinghua CHEN
- Publication Type:Journal Article
- Keywords:
Artificial kidney;
Renal osteopathy;
Hemodialysis;
Hemoperfusion;
Parathyroid hormone
- From:
Clinical Medicine of China
2010;26(5):465-467
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore therapeutic effects of combinative artificial kidney treatment on renal osteopathy.Methods HD + HP Group composed by 30 urinaemia was treated with hemodialysis and hemoperfusion,and the HD Group was treated only with hemodialysis.Clinical symptoms and lab indicators including osteodynia,itch of skin,blood pressure,appetite,sleep,as well as BUN,SCr,Hb,BPC,Ca,P and iPTH,were compared between the two groups.Results Osteodynia decreased by 67.7% (21/31),and itch of skin by 71.0% (22/31)in HD group.Osteodynia decreased by 96.7% (29/30) ,and itch of skin by 96.7% (29/30) in HD + HP group (P ＜0.01 ).iPTH were (65.5 ± 34.4) pmol/L before treatment and (57.1 ± 21.4) pmol/L after treatment in HD group,and (73.5 ± 44.4)pmol/L and (19.1 ± 17.4)pmol/L in HD + HP group.HD Group eliminated less iPTH (P ＞0.05).HD + HP Group removed more serum poison molecules than HD Group ( P ＜ 0.05 ).Conclusions For patients in maintenance-dialysis stage but with higher iPTH,hemodialysis combined with hemoperfusion removes more poison molecules,consequently decreases incidence of renal osteopathy.
