Clinical study on prophylactic treatment with Clostridium Butyricum Powder for preventing childhood diarrhea after pneumonia

VernacularTitle:酪酸梭菌活菌散预防小儿肺炎继发性腹泻的临床研究
Author: Lijuan FU ; Hongfu LI
Publication Type:Journal Article
Keywords: Pneumonia; Diarrhea; Clostridium Butyricum; Antibacterial
From: Chinese Journal of Primary Medicine and Pharmacy 2010;17(6):749-751
CountryChina
Language:Chinese
Abstract: ObjectiveTo observe and evaluate the efficacy of Clostridium Butyricum Powder for preventing childhood diarrhea after pneumonia. Methods176 infants with pneumonia were randomly divided into two groups,100 infants as prevention group, another 76 infants as control group. With normal antibacterial therapy,and two hours afterwards. Clostridium Butyricum Powder was administered at doses of 0.5g three times a day,in prevention group.After diarrhea taken place, Clostridium Butyricum Powder was administered at doses of 0. 5 g three times a day, in control group. Clinical effect and untoward effect were observed. ResultsThe incidence of pneumonia-induced diarrhea was 9% in prevention group,and was 46. 8% in control group( P < 0. 01 ). Duration of diarrhea and course of the treatment in prevention group as compared to those in the control group were statistically significant( P < 0. 01 ).Adverse reaction was not found. ConclusionClostridium Butyricum Powder can prevent diarrhea after pneumonia with antibacterial therapy.