The clinical value of serum IL-6 detection in patients with Graves

VernacularTitle:血清白细胞介素-6测定在Graves病中的临床意义
Author: Xia LI ; Shurong LUAN ; Xiuying GENG ; Xiaoli LIU ; Jing LI
Publication Type:Journal Article
Keywords: Grave disease; Interleukin-6
From: Clinical Medicine of China 2010;26(6):603-605
CountryChina
Language:Chinese
Abstract: Objective To study the clinical value of serum FL-6 detection in patients with Graves. Methods The level of IL-6 was detected in 75 Graves patients and controls with ELISA, the correlation between IL-6, other function parameter (T3, T4, etc.) and immune indicators (TRAb) were analyzed. Results The level of IL-6 in Graves patients was(1. 84 ±1. 58) ng/L, which was significantly higher than the healthy controls(l. 28 ±0.46)ng/L (t=2.55,P<0.05).IL-6 was positive correlation with T3(r =0. 55) ,T4(r =0. 40) ,FT4(r =0. 36) , FT3(r = 0. 35)and TRAb(r = 0. 47) (P <0. 05)and was negative correlation with TSH(r= -0. 58, P < 0. 05). Conclusions IL-6 can be used as a good index of immune derangement and thyroid function disorders in Grave patients.