High CD11b expression on monocyte and neutrophile granulocyte correlates with type 2 diabetes mellitus complicated with macroangiopathy
10.3760/cma.j.issn.1000-6699.2010.06.011
- VernacularTitle:单核细胞和中性粒细胞CD11b高表达与2型糖尿病及其大血管病变相关
- Author:
Yanling HUANG
;
Xiangjiu YANG
;
Hong MA
;
Qun HUANG
;
Yan ZHANG
;
Xiaomin CHEN
- Publication Type:Journal Article
- Keywords:
Monocytes;
Neutrophile granulocytes;
CD11b;
Daibetes mellitus,type 2;
Macroangiopathy;
Inflammation
- From:
Chinese Journal of Endocrinology and Metabolism
2010;26(6):474-475
- CountryChina
- Language:Chinese
-
Abstract:
The expression of CD11b on monocytes and neutrophils were measured by direct immunofluorescence techiques and flow cytometry in controls and type 2 diabetic patients.CD11b expression on monocyte and neutrophil in diabetic patients with macroangiopathy was higher than that in cases without macroangiopathy [3.85±1.46 vs 2.88±0.92,6.36 (4.58-9.79) vs 4.23 (3.70-4.83),both P<0.01].Monocyte CD11b and neutrophil CD11b might be independent risk factors of macroangiopathy in type 2 diabetes mellitus.
