Clinical value of thinprep cytology test combined with colposcopy in diagnosis of cervical lesion
10.3760/cma.j.issn.1008-6315.2010.06.030
- VernacularTitle:液基细胞学联合阴道镜在宫颈病变诊治中的临床应用
- Author:
Lili KONG
;
Lijing XUAN
;
Yanying LI
;
Limin ZHAO
- Publication Type:Journal Article
- Keywords:
Thinprep cytology test;
Cervical intraepithelial neoplnsia;
Colposcopy;
Biopsy
- From:
Clinical Medicine of China
2010;26(6):637-639
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of thinprep cytology test(TCT) combined with colposcopy in diagnosis of cervical lesion. Methods Retrospective analysis was conducted in 174 females with abnormal cervical smear. All the patients underwent colposcopy to screen the cervical lesions. According to the pathological results,the clinical value of TCT and colposcopy was analyzed and compared. Results In the 174 cases with abnormal cervical smear,the positive rate of atypical squamous cells(ASC) was 27. 0% (47/174). There were 92 low grade squamous intraepithelial lesion (LSIL) (52. 9%) ,33 high grade squamous intraepithelial lesion (HSIL) (19. 0%) and 2 squamous cell cancinoma (SCC) (1. 1%) . According to the diagnosis by biopsy and pathology,the positive rate of benign cervical cell(BCC) was 16. 1% (28/174) .cervical intraepithelial neoplnsia (CIN) I 42. 0% (73/174), CIN II 18.4% (32/174), CIN ffl 21. 8% (38/174) and SCC 1. 7% (3/174) . The coincidence rate of TCT and pathology was 83. 9% (146/174). Conclusions TCT and colposcopy are a practical approach for detecting cervical lesion. TCT combined with colposcopy is the optimal screening approach for cervical lesion, which can enhance the sensitivity and specificity of the diagnosis of cervical lesions.
