Dact genes involved in wnt and TGF-β signaling pathway and their relationship with tumorigenesis
10.3760/cma.j.issn.1673-4203.2010.06.020
- VernacularTitle:Dact基因参与wnt和TGF-β信号通路调控及其与肿瘤发生的研究
- Author:
Shoufu LI
;
Xiujun LIAO
;
Guangen YANG
- Publication Type:Journal Article
- Keywords:
Dact;
Wnt;
TGF-β;
Cell signal
- From:
International Journal of Surgery
2010;37(6):420-423
- CountryChina
- Language:Chinese
-
Abstract:
Dact proteins belong to a structure-related protein family. Recent studies have demonstrated that Dact proteins play an important role in tumorigenesis via modulation of wnt and TGF-p signaling. Delin-eation of the physiological function of Dact proteins would enhance our understanding of look for new strategy targets for cancer and suggests a potential strategy for therapeutic control of wnt and TGF-β signaling in canc-er.
