Pulmonary Infection after Kidney Transplantation.
- Author:
Samuel LEE
1
;
Dae Kyung KOH
;
Hyeon Cheol YEON
;
Ma Hae CHO
;
Joo Seop KIM
;
Young Cheol LEE
;
Ki Suck JUNG
;
Dong Wan CHAE
;
Hyung Jik KIM
;
Sang Wook HAN
;
Eun Sook NAM
;
Mi Hae KIM
;
Soo Tae KIM
;
Chang Sig CHOI
Author Information
1. Department of Surgery, Hallym University College of Medicine, Korea.
- Publication Type:Case Report
- Keywords:
Kidney transplantation;
Pulmonary infection
- MeSH:
Allografts;
Anti-Bacterial Agents;
Aspergillus;
Cytomegalovirus;
Female;
Hospitalization;
Humans;
Immunosuppression;
Kidney Transplantation*;
Kidney*;
Lung;
Male;
Mortality;
Nocardia;
Transplants
- From:The Journal of the Korean Society for Transplantation
1999;13(2):311-322
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The infectious complications after renal transplantation remain as an important causes of both mortality and graft loss. The lung is the most common target for post-transplant infection. We analyzed the causative agents, treatments and outcomes of post-transplant pulmonary infections. From 1990 to 1998, 192 renal allografts were performed at Hallym University Hospital. Seven cases (3.6%) of 5 males and 2 females developed serious pulmonary infections and required hospitalization. The mean age was 42.6 years. The onsets of pulmonary infections were from a month to 6 months in 3 cases, from 6 months to a year in one case and after a year in 3 cases. Triple therapy regimen was used in 4 cases as an immunosuppression therapy. Acute rejections developed in 6 cases. Causative organisms were Cytomegalovirus in 2 cases, Mycobacteria in 2 cases, Aspergillus in a case, Nocardia in a case and unknown in a case. Despite appropriate antibiotics, four patients did not respond to the treatment and died. The early recognition of infection and appropriate therapy is important to reduce fatal consequence.