Application of enteral nutritional support by needle catheter jejunostomy feeding tube during postoperative adjuvant chemotherapy of staged gastric cancer
10.3760/cma.j.issn.1673-4904.2010.12.012
- VernacularTitle:延期留置空肠造口管间断肠内营养在进展期胃癌术后辅助化疗中的应用评价
- Author:
Guosen SU
;
Jianwei ZHAN
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Adjuvant chemotherapy;
Needle catheter jejunostomy;
Enteral nutrition
- From:
Chinese Journal of Postgraduates of Medicine
2010;33(12):29-31
- CountryChina
- Language:Chinese
-
Abstract:
Objegtive To study the feasibility and clinical effects of enteral nutrition by needle catheter jejunostomy(NCJ)tube in the postoperative adjuvant chemotherapy for patients of staged gastric cancer.Methods Eighty-two patients with staged gastric cancer underwent radical gastrectomy and going to receive chemotherapy were randomly divided into group A(41 cases)and group B(41 cases).All of the patients had been NCJ.Group A received enteral nutrition through the tube during chemotherapy,and group B had been given general diet.A series of parameters were measured post-chemotherapy.And the gastrointestinal complications were carefully observed.Results In post-chemotherapy,the level of hemoglobin,albumin,prealbumin,interleukin-2,natural killer cell activities and CD3+,CDd4+,CD4/CD8 in group A[(106.9±12.0)g/L,(26.2±1.4)g/L,(202.9±32.2)mg/L,(11.9±2.1)μg/L,(21.3±5.2)%,(62.9±3.3)%,(26.1±4.7)%,1.1±0.2]were significantly higher than those in group B(P＜0.05 or＜0.01).The incidences of vomiting in group A(4.9%,2/41)was significantly lower than that in group B (26.8%,11/41)(P＜0.05).The average intake in group A[(1312±114)ml]was significantly more than that in group B[(76.5±186)ml](P＜0.05).No severe enteral nutrition related complications occurred in group A.Conclusions It is safe and feasible to enteral nutrition supported by NCJ tube in chemotherapy for patients of staged gastric cancer.It can improve the nutrition status and immune function in the given patients.
