Changes of microalbunminuria(MAU) levels in mechanical ventilated patients with severe pneumonia and the clinical significance on prognosis of these patients

VernacularTitle:机械通气对重症肺炎患者尿微量白蛋白水平的影响
Author: Haiying ZHOU ; Shufang MENG ; Yi ZHOU ; Jinyin CHEN ; Yumiao ZHANG
Publication Type:Journal Article
Keywords: Pneumonia; Microalbunminuria
From: Chinese Journal of Primary Medicine and Pharmacy 2010;17(8):1064-1066
CountryChina
Language:Chinese
Abstract: Objective To evaluate the clinical significance of the changes of microalbunminuria(MAU) levels in mechanical ventilated patients with severe pneumonia. Methods According to the ratio between the microalbunminuria and the urine creatinine (MAU/CR) (ACR), setting 25mg/mmol as the threshold, 78 mechanical ventilated patients with severe pneumonia were divided into two groups :ACR increasing group and ACR Non-increasing group,then the clinical significance of changes of MAU levels in 72 hours on prognosis of these patients was observed. Results MAU increased in 64 cases(82. 1%) ,of which 46 cases in ACR increasing group and 18 cases in ACR non-increasing group. There showed statistically significant differences on APACHE Ⅱ score, CPIS score,PCT、the success of getting out of mechanical ventilation and the mortality between two groups, (t = 3.50、2. 19 、x~2 = 3. 95、6. 70、5.38 ,P = 0.01,0.03,0.04,0.01,0.02, all P ＜ 0.05). Conclusion Changes of MAU levels have the clinical significance on prognosis of the mechanical ventilated patients with severe pneumonia.