The clinical effect of Redlining injection on acute lung injury
10.3760/cma.j.issn.1008-6706.2010.10.012
- VernacularTitle:热毒宁注射液治疗急性肺损伤的临床疗效
- Author:
Fenghua QIAN
;
Yiming QIAN
;
Liang ZHU
;
Zhibing XU
;
Lili QI
;
Lei ZHAO
- Publication Type:Journal Article
- Keywords:
Respiratory distress syndrome,adult;
Reduning injection;
Positive-pressure respiration
- From:
Chinese Journal of Primary Medicine and Pharmacy
2010;17(10):1318-1319
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical effect of the lung protective ventilation combining with Re-duning injection on the acute lung injury (ALI). Methods 59 patients with ALI were randomly divided into the lung protective ventilation group (control group, n =30) and the lung protective ventilation wmbined with Reduning injection group(experimental group,n = 29) ,and the changes of vital signs,RR,blood gas analysis,and so on were observed. The comparison between PaO2 and PaO2/FiO2 was carried out. The efficacy and the mortality rate were evaluated. Results Lung injury in 21 cases of experimental group were improved after applied Reduning treatment(72. 41%),there was a significant difference ( P < 0.05) with that of 14 cases in control group (46. 67% ) ; PaO2 increased, PaO2/FiO2 significantly increased in experiment group,there were significant difference compared with those of control group(P <0. 01). The mortality rate in the experimental group was 24.14% ,there was a significant differ-ence(P<0.05) compared with the mortality of 50. 00% in control group. Conclusion Reduning treatment could, improve the pulmonary function in lung protective ventilation to cure ALI,reducing the mortality rate as well.
