The efficacy of captopril combined with methylprednisolone for treatment of RNS
10.3760/cma.j.issn.1008-6706.2010.09.018
- VernacularTitle:卡托普利联合甲泼尼龙治疗难治型肾病综合征疗效观察
- Author:
Ping YU
- Publication Type:Journal Article
- Keywords:
Nephrotic syndrome;
Captopril;
Methyprednisolone
- From:
Chinese Journal of Primary Medicine and Pharmacy
2010;17(9):1187-1188
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the efficacy of captopril and methylprednisolone in the implosive therapy of RNS.Methods 21 cases of RNS who have captopril 1.25 mg/d and intravenous dripping methylprednisolone of 20mg/kg·d sustained 1-2h for 3 days,if non-remissions,using once more after a week.Results 21 cases of children with complete remission in 13 cases,partial remission in 5 cases,non-remission in 3 cases.The overall response rate was 86%.In complete remission 13 cases,4 cases remission after 2 courses treatment,5 cases remission after four courses treatment,4 cases remission after 6 courses treatment.Conclusion Combined captopril with methylprednisolone in treating refractory nephritic syndrome can improve the rate of remission.
