Effect of salvia mihiorrhiza on spinal cord ischemia reperfusion injury after surgical treatment

VernacularTitle:丹参预防脊柱外科术后脊髓缺血再灌注损伤的疗效观察
Author: Ling ZHAO ; Jian WANG ; Zhonghua YANG ; Jianhua ZHANG ; Qing CUI
Publication Type:Journal Article
Keywords: Salvia mihiorrhiza; Spinal cord ischemia reperfusion injury
From: Clinical Medicine of China 2010;26(6):628-630
CountryChina
Language:Chinese
Abstract: Objective To investigate the effect of salvia mihiorrhiza on spinal cord ischemia reperfusion injury after surgical treatment in patients with cervical canal stenosis. Methods Retrospective analysis of 64 cases had cervical canal stenosis in the last 5 years in our hospital. Sixty-four cases were randomly divided into the salvia mihiorrhiza group(31 cases)and the control group(33 cases). The therapeutic effect was assessed using JOA grade system. Results In the salvia mihiorrhiza group,the JOA average score was 8. 8 ±2. 6 before surgical treatment, after two weeks of surgical treatment it was 13. 7 ± 2. 4. The JOA improvement ratio was (61. 5 ± 2. 9) % . In the control group,the JOA average score was 9. 1 ±2. 2 before surgical treatment,after two weeks of surgical treatment it was 13. 4 ± 2. 3. The JOA improvement ratio was (60. 5 ± 2.2)% .The JOA improvement ratio in the salvia mihiorrhiza group was significantly higher than that in the control group (P < 0. 05) . Conclusions Salvia mihiorrhiza has protective effect on spinal cord ischemia reperfusion injury.