Clinical observation of racecadotril granules in treating rotaviral enteritis in infants

VernacularTitle:消旋卡多曲辅助治疗儿童轮状病毒肠炎的临床观察
Author: Qingyuan LI
Publication Type:Journal Article
Keywords: Rotavirus infections; Racecadotril graules; Child
From: Chinese Journal of Primary Medicine and Pharmacy 2010;17(8):1043-1044
CountryChina
Language:Chinese
Abstract: Objective To investigate the curative effect of racecadotril granules on acute rotaviral enteritis in infants. Methods 100 infants with acute rotaviral enteritis were divided into combined treatment group(group A:50)cases and smecta group(B group:50 cases) ;Group B was given to basis of conventional therapy,but Group A received conventional therapy combined with clothing racecadotril particles. The efficacy and adverse reactions were observed.Results The time of improvement of vomiting,fever and diarrhea in A group was significantly shorter than the B group(t =2. 245,2. 298,2. 301, all P ＜ 0.05); The total effective rate 92. 0% in A group were higher than the B group 74. 0% after treatment 3d(x~2 = 3.987, P ＜ 0.05). The average course of treatment in A group (5.5 ± 0. 9) d was lower than the B group(7. 0 ± 1.1)d(t =7.17,P＜0.01). Conclusion Racecadotril is an effective and safe drug in treating rotaviral enteritis in infants.