Diagnosis and treatment of female pseudohermaphroditism
10.3760/cma.j.issn.1673-4904.2010.12.004
- VernacularTitle:女性假两性畸形诊断和治疗
- Author:
Xiaojun XIE
- Publication Type:Journal Article
- Keywords:
Female;
Pseudohermaphroditism;
Adrenal hyperplasia,congenital;
Diagnosis;
Therapy
- From:
Chinese Journal of Postgraduates of Medicine
2010;33(12):8-10
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the etiology,clinical features,diagnosis and treatment measures of female pseudohermaphroditism.Methods Five Cases,of female pseudohermaphroditism were collected.The etiology,clinical features,diagnosis and treatment measures were discussed.Results One case induced by exogenous androgenic hormones,4 cases induced by congenital adrenal hyperplasia.All the 5 cases presented with abnormal development of vulva and the sex chromosomes karyotype of 46XX.The combined treatment ofreconstructive surgery (5 cases)and supplementary glucocorticoid (4 cases)wefe performed.After 3months,the levels of adrenocorticotrophic hormone and virosterone were normal.Followed up for 1-10 years,The postoperative appearance of external genitalia was similar to the normal.The secondary sex characters were improved obviously,3 cases were mainly feminilism,2 cases existed different degree of psychologic obstacle.Conclusions The diagnosis and treatment in the early stage are very important.The combination treatment of surgery and medicine for the patients with female pseudohermaphroditism is satisfied.
