The analysis and the prevention of nosocomial infection and the risk factors in senile patients with acute myelogenous leukemia after chemotherapy
10.3760/cma.j.issn.1672-7088.2010.05.073
- VernacularTitle:老年急性髓系白血病患者化疗后医院感染病原学、危险因素分析及预防
- Author:
Qi XU
;
Jiaqi ZHANG
;
Tie CHAI
;
Jing WANG
;
Jun LI
;
Yanchun LIU
;
Ming CONG
- Publication Type:Journal Article
- Keywords:
Senile;
Acute leukemia;
JVosocomial infection;
Nursing
- From:
Chinese Journal of Practical Nursing
2010;26(14):50-52
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the etiology of nosocomial infection and the risk factors in senile patients with acute myelogenous leukemia who received chemotherapy, then to explore the preventive measure. Methods 9lcases of senile patients with AML received 304 times of chemotherapy, then to analyze the rate of nosocomial infection, the infection site, the result of etiological examination and the relationship between the rate of nosocomial infection and the absolute of neutrophil count in peripheral blood and the duration of agranulocytosis. And then the results were compared with the non-senile patients with AML. Results The statistical indicators of nosocomial infection in senile patients with AML was higher than those younger ones. The rate of infection in lower respiratory tract, oral, alimentary canal, skin, anal area and the rate of sepsis in senile people was higher than those younger ones.Positive rate of fungal infection of senile patients was higher. The nosocomial infection in the patients whose absolute neutrophil count in peripheral blood was no more than 0.5×l09/L,and prolonged over 7 days was specific higher. Conclusions Senile patients with AML is the high risk group for nosocomial infection. Age, chemotherapy, the neutrocytopenia level and prolonged time are related to the nosocomial infection in senile patients with AML. It is necessary to take positive measure to control nosocominal infection and advance life quality of senile patients.
