Human cervical cancer oncogene and tumor
10.3760/cma.j.issn.1673-422X.2009.12.001
- VernacularTitle:人宫颈癌基因与肿瘤
- Author:
Linhua YAO
;
Guoxin ZHANG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Tumor marker;
biology;
Human cervical cancer oncogene
- From:
Journal of International Oncology
2009;36(12):883-885
- CountryChina
- Language:Chinese
-
Abstract:
Human cervical cancer oncogene(HCCR) is newly identified in cervical cancer tissues,and expresses in most human tumors. Resarches show that HCCR is a candidate marker for human hepatocelular carcinoma and breast cancer. Moreover,the expression of HCCR is regulated by mitogen-activated protein kinase (MAPK)and phosphatidylinositol 3-kinase signal pathway. The proliferation,apoptosis,migration and invasion of tumor cells could be inhibited by siRNA of HCCR.
